The luxury midsize vehicle market is a battleground for some of the most prestigious automakers in the world. At the heart of this competition stands the Mercedes-Benz E-Class, which continues to set the standard for elegance, performance, and cutting-edge technology with its 2025 E 350 model. But how does the E 350 stack up against one of its rivals, the Lexus RX? Let's dive into a detailed comparison of these two luxury vehicles.
Design and Exterior
The 2025 Mercedes-Benz E 350 showcases a sleek, aerodynamic profile that seamlessly blends classic Mercedes styling with modern flair while maintaining practicality. For example, its LED headlights and taillights not only provide excellent visibility but also add to its striking appearance. The AMG exterior styling highlights its sporty performance, and the chrome and gloss black star-pattern grille adds an elevated touch.
In contrast, the Lexus RX boasts a bold spindle grille design and more angular, aggressive styling. While both vehicles command attention on the road, the E 350's elegant proportions and flowing lines offer a timeless appeal that many find irresistible.
Interior and Comfort
Inside the E 350, you're greeted by a cabin that exemplifies luxury with leather-like MB-Tex upholstery and heated front seats that are power-controlled with lumbar support and memory functions. The spacious interior provides an ample 41.5 inches of legroom to ensure comfort for front passengers on long journeys and a respectable 12.7 cubic feet of cargo space. If you're looking for even more sophistication, explore the multitude of optional upgrades, from massage seats to air fragrance and purification systems.
The Lexus RX also offers high-quality materials and craftsmanship, with comfortable seating and available leather upholstery. However, the E 350 edges ahead in overall refinement and attention to detail with its Black Ash wood trim and 64 LED light colors that let you create highly customizable ambient lighting for any mood.
Performance and Powertrain
Under the hood, the 2025 Mercedes-Benz E 350 houses a turbocharged 2.0L inline-4 engine that delivers impressive performance. With 255 horsepower at 5,800 rpm and 295 lb-ft of torque kicking in at just 2000 rpm, it provides robust acceleration and effortless cruising. The E 350 can sprint from 0 mph to 60 mph in a mere 6.1 seconds, whereas the Lexus RX takes 7.6 seconds.
The E 350's power is channeled through a refined nine-speed automatic transmission, offering smoother shifts and optimal fuel efficiency compared to the Lexus RX's eight-speed transmission. For those seeking enhanced traction and stability, the available 4MATIC all-wheel-drive system is a worthwhile upgrade, especially for regions with inclement weather.
The Lexus RX offers various engine options, including hybrid powertrains, which may appeal to the eco-conscious buyer. However, the E 350's balanced approach to performance and efficiency makes it a compelling choice for those who appreciate a dynamic driving experience.
Fuel Economy
Despite its potent performance, the Mercedes-Benz E 350 doesn't compromise on efficiency. Its EPA estimates stand at an impressive 25 mpg in the city and 33 mpg on the highway. When you compare these numbers to the Lexus RX's estimates of 22 mpg in the city and 29 mpg on the highway, it's clear that Mercedes-Benz is committed to engineering excellence.
Handling and Ride Quality
The 2025 E 350 comes equipped with an adaptive suspension system and multiple driving modes, including Comfort, Sport, and Eco, to suit a variety of road conditions. For even more flexibility, you can create your own unique mode or switch to manual shifting with the “Individual” selection. The Lexus RX, especially with its available F SPORT handling package, provides a comfortable ride, but it tends to prioritize comfort over sportiness. The E 350, on the other hand, manages to excel in both areas, offering a more engaging driving experience overall.
Safety Features
Safety is paramount in the luxury vehicle market, and the Mercedes-Benz E 350 doesn't disappoint. Standard features include Active Brake Assist, which can help prevent collisions, and ATTENTION ASSIST, which monitors driver behavior for signs of fatigue. The Lexus RX comes with its own suite of safety technologies, including the Lexus Safety System+ 3.0, but the E 350 also offers a host of optional driver-assistance features for those looking for extra peace of mind, such as the PRE-SAFE PLUS system that proactively protects occupants in the event of an impending collision.
Infotainment and Technology
At the heart of the E 350's technology offerings is the MBUX infotainment system. This cutting-edge interface features a 14.4-inch, high-resolution screen with intuitive controls and advanced voice recognition capabilities, blowing the Lexus RX's 9.8-inch touchscreen out of the water. Both models offer smartphone integration via Apple CarPlay and Android Auto, ensuring seamless connectivity on the go.
Audiophiles will appreciate the E 350's optional Burmester 4D sound system, which transforms the cabin into a concert hall on wheels, delivering crisp, immersive sound through 17 high-end speakers. While the Lexus RX offers its own 12-speaker premium sound system, many find the MBUX system more user-friendly and feature-rich.
Pricing and Trim Levels
The 2025 Mercedes-Benz E 350 starts at $62,450, a competitive price that positions it well within the luxury midsize segment. Various trim levels and packages, from performance enhancements to luxury upgrades, allow buyers to customize their E 350 to their exact specifications. While the Lexus RX may offer a lower starting price for some models, the E 350's combination of performance, luxury, and technology provides exceptional value for discerning buyers.
Reliability and Maintenance
Both Mercedes-Benz and Lexus have strong reputations for building reliable vehicles. Mercedes-Benz's commitment to innovation often means incorporating the latest technologies, which can sometimes lead to higher maintenance costs down the road. Purchasing from an authorized dealer, such as Mercedes-Benz of State College, ensures access to factory-trained technicians and genuine parts to maximize your vehicle's longevity and performance and save you money in the long term.
The Mercedes-Benz Advantage
While the 2025 Mercedes-Benz E 350 and the Lexus RX both offer comfort and reliability, the E 350 is a compelling choice with its perfect balance of elegance, cutting-edge technology, and driving dynamics. To truly appreciate the E 350's capabilities, there's no substitute for personal experience. Contact us at Mercedes-Benz of State College to schedule a test drive and experience the difference that comes with driving a Mercedes-Benz — where luxury meets performance and innovation meets tradition. Our knowledgeable staff can guide you through the E 350's features and help you configure a model that perfectly suits your needs and preferences.
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